Phorbol 13-butanoate

Author: vjxe

August undefined, 2024

WebThe enzyme phorbol-diester hydrolase (EC 3.1.1.51) catalyzes the reaction phorbol 12,13-dibutanoate + H 2 O phorbol 13-butanoate + butanoate. This enzyme belongs to the … WebMar 30, 2024 · We have previously found that the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) induces specific transcription of tRNA and 5S RNA genes in Drosophila Schneider S-2 cells (M. Garber, S. Panchanathan, R. F. Fan, and D. L. Johnson, J. Biol. Chem. 266:20598-20601, 1991). Having derived cellular extracts from TPA-treated cells, that are …

phorbol 13-butanoate (CHEBI:17727)

WebGene Ontology Term: phorbol-diester hydrolase activity GO ID GO:0050181 Aspect Molecular Function Description Catalysis of the reaction: H2O + phorbol 12,13-dibutanoate = … WebThe effects of n-butyrate and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) on both EBV-antigen induction and cell differentiation in two virus-nonproducer lymphoblastoid cell lines, Raji and NC37, were now studied. The following observations were made (1). On its own either drug induced 1–2 per cent of cells to EBV-early-antigen positivity in ... grammar schools in bromley borough

KEGG COMPOUND: C03019 - Genome

WebFind Safety Data Sheets(SDS) of PHORBOL 13-BUTYRATE, 4BETA(CAS 100929-94-0 ) for lookchem WebApr 1, 1993 · The in vivo binding properties of this compound to protein kinase C were confirmed by in vivo displacement studies with unlabeled 12-deoxyphorbol 13-isobutyrate-20-butyrate and unlabeled phorbol ... WebThe precursor protected in the 20-hydroxyl group of phorbol was acylated by [1-11 C]propyl ketene to the 13-hydroxyl group producing phorbol 13-[11 C]butyrate ([11 C]P13Bu). Total … china silver glass coffee table

ENZYME - 3.1.1.51 phorbol-diester hydrolase

WebPhorbol 12,13-dibutyrate (PDB), a potent activator of protein kinase C … Polymyxin B, a selective inhibitor of protein kinase C, diminishes the release of noradrenaline and the enhancement of release caused by phorbol 12,13-butyrate Naunyn Schmiedebergs Arch Pharmacol. 1986 Oct;334(2):218-21. doi: 10.1007/BF00505825. ... WebPhorbol 13-butanoate CAS Number: 100929-94-0: Molecular Weight: 434.52300: Density: N/A: Boiling Point: N/A: Molecular Formula: C 24 H 34 O 7: Melting Point: N/A: MSDS: N/A … china silver production 2022WebUsing BCBL-1 cells that harbour HHV-8 but lack Epstein-Barr virus, we demonstrate that sodium butyrate is much more effective than the phorbol ester 12-O-tetradecanoyl … grammar school registration birmingham

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Phorbol 13-butanoate

WebC03019 Phorbol 13-butanoate. BRITE hierarchy: Other DBs: PubChem: 5925: ChEBI: 17727: ChEMBL: CHEMBL3586005: NIKKAJI: J366.990D: KCF data: Show. ATOM 31 ... 18 13 19 2 … WebSYMPTOMS: This material may cause skin irritation. ACUTE/CHRONIC HAZARDS: This compound may cause irritation upon contact with skin. (NTP, 1992) Reactivity Profile This material may be sensitive to prolonged exposure to air, light and ambient temperatures. It may also be subject to autooxidation. (NTP, 1992)

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WebPhorbol 12,13-dibutyrate is a phorbol ester which is one of the constituents of croton oil. As an activator of protein kinase C, it is a weak tumor promoter compared to 12-O … WebDec 27, 2012 · Interestingly, phorbol esters, similar to butyrate, exhibit differentiating potential involving activation of PKC . Phorbol esters such a phorbol-12-myristate-13- acetate (PMA) are useful experimental analogs of diacylglycerol, the physiological activator of PKC [27] also exhibiting the potential to activate MAPK [28] and, as a consequence, the ...

Webphorbol 12,13-dibutanoate: ChEBI ID CHEBI:17598: Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:8117, CHEBI:14789, … WebJul 1, 2002 · The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process

WebChemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on 'small' chemical compounds. phorbol 13-butanoate (CHEBI:17727) … WebWe studied the ability of inducers and inhibitors of erythroid differentiation of K562 leukemia cells, such as sodium butyrate, dimethyl sulfoxide, and phorbol-12-myristate-13-acetate, respectively, to modulate sensitivity of these cells to nonspecific lysis (nonrestricted with respect to antigens of the major histocompatibilty complex) mediated by natural human …

WebApr 23, 2024 · phorbol 12,13-dibutanoate + H 2 O → butanoate + phorbol 13-butanoate + H + Summary: Hydrolyses the 12-ester bond in a variety of 12,13-diacylphorbols (phorbol is a diterpenoid); this reaction inactivates the tumour promotor 12-O-tetradecanoylphorbol-13-acetate from croton oil.

WebPhorbol 12,13-dibutyrate C28H40O8 CID 37783 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... china silver spray bottleWebOct 2, 2003 · Therefore, the present studies were undertaken to examine whether hydrocortisone and phorbol 12-myristate 13-acetate (PMA) are involved in a possible regulation of the butyrate/anion exchange process in Caco-2 cells. The butyrate/anion exchange process was assessed by measuring a pH-driven [(14)C]butyrate uptake in … grammar schools in fremont caWebPhorbol 12,13-dibutanoate + H2O <=> Phorbol 13-butanoate + Butanoic acid. Equation: C03634 + C00001 <=> C03019 + C00246 grammar schools in kent county councilWeb(NTP, 1992) Health Hazard SYMPTOMS: This material may cause skin irritation. ACUTE/CHRONIC HAZARDS: This compound may cause irritation upon contact with skin. … china sim card numberPhorbol 13-butanoate C24H34O7 CID 439882 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. grammar schools in medwayhttp://aammt.tmmu.edu.cn/html/202412057.htm grammar schools in lincolnshireWebphorbol-diester hydrolase Alternative Name(s) diacylphorbate 12-hydrolase: Reaction catalysed; H2O + phorbol 12,13-dibutanoate => butanoate + H(+) + phorbol 13-butanoate: … grammar schools in london for boys