Klf9 cyp1a1
WebApr 29, 2024 · Here, we show that hepatic Krüppel-like factor 9 (Klf9) gene expression is induced by dexamethasone and fasting. The overexpression of Klf9 in primary hepatocytes strongly stimulated Pgc1a gene expression through direct binding to its promoter, thereby activating the gluconeogenic program. WebSep 9, 2024 · The identification of klf9 as a key regulator of the physiological response to cortisol builds on earlier research in which Coffman showed that chronic exposure to cortisol early in life has...
Klf9 cyp1a1
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WebJun 26, 2009 · HGNC Approved Gene Symbol: KLF9 Cytogenetic location: 9q21.12 Genomic coordinates (GRCh38): 9:70,384,604-70,414,657(from NCBI) TEXT Cloning and Expression … WebJan 1, 2024 · Title: KLF9 and EPYC acting as feature genes for osteoarthritis and their association with immune infiltration. Circular RNA_0078767 upregulates Kruppel-like factor 9 expression by targeting microRNA-889, thereby inhibiting the …
WebSep 29, 2024 · The Klf9 cDNA was inserted into vector containing the 5.4-kb adiponectin promoter. Mouse oocytes were injected with this construct at Beijing Biocytogen Co., Ltd. Global Ucp1 mutant mice were kindly provided by Dr. Yifu Qiu (Institute of Molecular Medicine, Peking University). WebKLF9, first recognized as a transcriptional repressor of the rat Cyp1a1, can modulate diverse biological processes to affect the progression of various diseases . Evidence has …
WebSep 21, 2024 · The common upregulated transcripts were transcription factors KLF9 (general regulatory element), FOXO3 (linked to apoptosis), ZFHX3 (thought to have a role in inhibiting the cell cycle) and CHI314 (which has been linked to intracellular infection and a Th2 inflammatory response). ... CYP1A1: −2.674: RNU12: −3.012: CLPS: −2.520: … WebDec 1, 2014 · Krüppel-like factor 9 (KLF9) is known to be a tumor suppressor gene in colorectal tumors and glioblastoma; however, the functional status and significance of …
WebNov 16, 2024 · KLF9 was verified to be directly regulated by TH in a TH receptor (TR)-dependent manner both in vivo and in vitro. Furthermore, knockdown of klf9 in zebrafish embryos impaired hematopoietic development including erythroid maturation and T …
WebKLF9, first recognized as a transcriptional repressor of the rat Cyp1a1, can modulate diverse biological processes to affect the progression of various diseases [ 6 ]. Evidence has emerged to suggest that knockdown of KLF9 can reduce hyperglycemia [ 7 ]. csuf business programs goodWebJun 1, 2007 · Klf9 was first isolated as a transcriptional inducer of the hepatic CYP1A1 gene . Later work identified stimulatory roles in vitro for Klf9 in neuronal cell differentiation and … early signs of pregnancy vs periodWebApr 29, 2024 · KLF9 activates the gluconeogenic program in primary hepatocytes through PGC1α. ( A) Quantitative PCR analysis showing mRNA levels of Pgc1a, G6pc, Pck1, and Glut2 in mouse primary hepatocytes infected with Ad-GFP or Ad-Klf9. Cells were harvested for further analysis 48 hours after infection. csuf campus jobsWebApr 13, 2024 · Krüppel-like factor 9 (Klf9) is a zinc finger transcription factor that functions in neural cell differentiation, but little is known about its genomic targets or mechanism of … early signs of pregnancy painWebJun 18, 2012 · Klf9 has been associated with differentiation and proliferation in mouse uterus epithelial tissue . However, a role for Klf9 in epidermal homeostasis has not yet … early signs of pregnancy ukWebFGF9: A gene on chromosome 13q11-q12 that encodes fibroblast growth factor 9 of the FGF family, which bind heparin and have a broad range of cellular activities, including cell … early signs of pregnancy hiccupsWebEffects of gestational exposure to bisphenol A on the hepatic transcriptome and lipidome of rat dams: Intergenerational comparison of effects in the offspring. csuf canvas dashboard