C3h/hej マウス
Webリポ多糖 / il-6 / 線維芽細胞 / c3h / hejマウス: 研究概要: c3h/hejマウスは、リポ多糖(lps)に著しく低応答性であり、このマウスのlps低応答性に関わる変異分子は第4染色体上に … WebC57BL/6 (C57 black 6、C57、black6; 略称: B6 )は、一般的な 近交系 実験用マウス である。. ヒトの疾患のモデルとして使用される遺伝子改変マウスの「遺伝的背景」として最も広く使用されている。. 遺伝的背景が同一の血統が入手可能であること、交配が容易で ...
C3h/hej マウス
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WebJul 27, 2024 · Detailed Description This general purpose strain shares a common origin with C3H/HeJ and C3H/HeOuJ. Unlike C3H/HeJ, it carries a normal allele at the Tlr4 locus, … WebThe C3H/HeJ mouse AA model induced via transferring cultured lymphoid cells isolated from AA-affected mice is widely used for AA research. However, this conventional …
WebMar 22, 2024 · 因此,C3H/HeJ (Tlr4Lps-d)對 革蘭氏陰性菌 (如沙門氏菌)高度敏感。. 感染 沙門氏菌 的小鼠表現為 趨化因子 產生延遲,NO生成損害以及細胞免疫應答減弱。. 感染的小鼠死亡原因主要是因為Kupffer細胞的網狀結構被大量增殖的細菌所破壞。. 應用領域:癌 … WebThe C3H/HeJ model has long dominated basic alopecia areata (AA) in vivo research and has been used as proof-of-principle that Jak inhibitors are suitable agents for AA …
WebThe C3H/HeJ mouse AA model induced via transferring cultured lymphoid cells isolated from AA-affected mice is widely used for AA research. However, this conventional method requires the continuous breeding of AA mice.
http://www.informatics.jax.org/inbred_strains/mouse/docs/C3H.shtml
WebC3H/He- Avy. Congenic line developed by backcrossing the Avy to the C3H background. Has an exceptionally high mammary tumour incidence, virtually 100% at 7-8 months. The fostered substrain C3H- Avy f B has a 90% incidence of mammary tumours transmitted by either parent ( Vlahakis et al., 1970 ., 1970). bom weather ballarat radarWebC3H/HeJ mice are highly susceptible to infection by Gram-negative bacteria such as Salmonella enterica. The C3H substrains at The Jackson Laboratory are homozygous for the retinal degeneration 1 mutation ( … gng scaffolding downham marketWebDec 11, 1998 · More than 30 years ago, mice of the C3H/HeJ strain were found to have a defective response to bacterial endotoxin (4–8). Inquiry into the genetic basis of LPS resistance revealed a single locus (Lps), wherein homozygosity for a codominant allele (Lps d) was responsible for the endotoxin-unresponsive state.The Lps d mutation arose in … bom weather ayrWebC3H/HeJマウスにおける円形脱毛症を開始するための可能性のある重要なプレーヤーとしての形質細胞様樹状細胞 Plasmacytoid dendritic cells as a possible key player to initiate alopecia areata in the C3H/HeJ mouse 出版者サイト 複写サービス 高度な検索・分析はJDreamⅢで 著者 (6件): Ito Taisuke ( Department of Dermatology, Hamamatsu … bom weather app for windowshttp://www.jslc.co.jp/pdf/mouse/007_c3hhen2007.pdf bom weather ballarat vicWebThe C3H/HeJBir mouse model: a high susceptibility phenotype for colitis C3H/HeJBir is a substrain of C3H/HeJ mice that was generated by selective breeding for the phenotype of spontaneous colitis. These mice show increased B cell and T cell reactivity to antigens of the enteric bacterial flora. bom weather archivesWebC3H. アルビノマウス (BALB)のメスとdbaのオスの交雑を行い、乳ガンの発症率の高い近交系としてC3H系が作出された。. 各種免疫主要関係試験、育毛関係試験で使用されている。. 遺伝的に網膜異常が見られる。. LPSに対して応答性が低い。. bom weather bawley point